The First Nations Health Consortium, the University of Alberta, and the University of Calgary have signed a memorandum of relational understanding to launch a collaborative Indigenous-led research partnership. The purpose of this collaboration is to improve health outcomes for children and families from treaty First Nations in Alberta. The signed agreement establishes a framework for joint research, knowledge-sharing, and innovation, and identifies the key areas of collaboration in community-led health research, capacity-building, innovation and technology integration, and policy engagement. “We are committed to a model of research that is community-driven and accountable,” said UCalgary Provost and VP (Academic) Sandra Davidson. “In this model, universities play an important role in supporting and amplifying Indigenous sovereignty in knowledge creation and application.”